El valor de los autoanticuerpos: de la teoria al laboratorio clinico

Christian Blas La Rosa Fabian

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Resumen

La prueba de autoanticuerpos es cada vez más relevante en el diagnóstico de las enfermedades autoinmunes. Como consecuencia, la detección de autoanticuerpos se reconoce cada vez más en los criterios de clasificación y las directrices de diagnóstico. Es importante conocer la presencia de los autoanticuerpos naturales y las características que permiten su diferenciación con los autoanticuerpos patológicos. Varias características especiales de los auto anticuerpos y el desarrollo de nuevas metodologías hacen que la interpretación correcta de los resultados de las pruebas de anticuerpos sea cada vez más difícil. En este artículo se revisa las características del autoanticuerpo, su reconocimiento como un analito heterogéneo y su implicancia en los métodos de detección, asi como la utilidad en la práctica clínica. 

Palabras clave

autoanticuerpos; enfermedad autoinmune; métodos inmunológicos; laboratorio clínico

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DOI: http://dx.doi.org/10.5281/zenodo.1173741

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